Yes I have done such on a neighbor’s Buick, but with the conveter backed off and the flex plate off for good access.
A sprayed down that whole area with carb cleaner and also right into the pan to main cap gap , let that all evaporate off for 2 hours and then layed on blue gasket maker and packed it in.
Then let that all set up for 2 full days due to no motor heat.
Last step was touching up the paint due to the carb cleaner removing it.
Just to reiterate, the key here is good access and total oil film removal!
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I do stuff for reasons.
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