Back when Pontiac Drag Days was a thing, we had a racer with a '67 GTO with I think a 421 with a Doug Nash 5-speed and a 4-pinion diff in the '67 rear end. His favored launch technique was to side-step the clutch at 6k rpm. He broke axles in that car almost every month, but never hurt the 4-pinion. One year he decided to "step up" to a 12-bolt with unknown internals. First pass, blew it up.
Obviously, that's one data point and YMMV...
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